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Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo
Senescence is a distinct cellular response induced by DNA-damaging agents and other sublethal stressors and may provide novel benefits in cancer therapy. However, in an ageing model, senescent fibroblasts were found to stimulate the proliferation of cocultured cells. To address whether senescence in...
Autores principales: | Ewald, J A, Desotelle, J A, Almassi, N, Jarrard, D F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359629/ https://www.ncbi.nlm.nih.gov/pubmed/18349844 http://dx.doi.org/10.1038/sj.bjc.6604288 |
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