Dual inhibition of EGFR and VEGFR pathways in combination with irradiation: antitumour supra-additive effects on human head and neck cancer xenografts

The aim of this study was to investigate the effects of combining antiangiogenic treatment, epidermal growth factor receptor (EGFR) targeting and irradiation (RT). We evaluated AZD2171, a highly potent, orally active, vascular endothelial growth factor (VEGF) signalling inhibitor, gefitinib, an EGFR...

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Detalles Bibliográficos
Autores principales: Bozec, A, Formento, P, Lassalle, S, Lippens, C, Hofman, P, Milano, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359670/
https://www.ncbi.nlm.nih.gov/pubmed/17592499
http://dx.doi.org/10.1038/sj.bjc.6603791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359670/
https://www.ncbi.nlm.nih.gov/pubmed/17592499
http://dx.doi.org/10.1038/sj.bjc.6603791

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