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Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies
There is increasing evidence of a systemic inflammatory response associated with malignancy, which may have an impact on both drug disposition and resistance to cytotoxic therapy. The impact of inflammation on drug disposition was studied in mice bearing a number of common tumour xenografts. C57BL/6...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359691/ https://www.ncbi.nlm.nih.gov/pubmed/18059400 http://dx.doi.org/10.1038/sj.bjc.6604101 |