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Dendritic Cells are preferentially targeted among hematolymphocytes by Modified Vaccinia Virus Ankara and play a key role in the induction of virus-specific T cell responses in vivo

BACKGROUND: Modified Vaccinia Ankara (MVA) is a highly attenuated strain of vaccinia virus (VV) that has lost approximately 15% of the VV genome, along with the ability to replicate in most mammalian cells. It has demonstrated impressive safety and immunogenicity profile in both preclinical and clin...

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Detalles Bibliográficos
Autores principales: Liu, Luzheng, Chavan, Rahul, Feinberg, Mark B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359732/
https://www.ncbi.nlm.nih.gov/pubmed/18412969
http://dx.doi.org/10.1186/1471-2172-9-15