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Synergistic effects of high fat feeding and apolipoprotein E deletion on enterocytic amyloid-beta abundance

BACKGROUND: Amyloid-β (Aβ), a key protein found in amyloid plaques of subjects with Alzheimer's disease is expressed in the absorptive epithelial cells of the small intestine. Ingestion of saturated fat significantly enhances enterocytic Aβ abundance whereas fasting abolishes expression. Apolip...

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Detalles Bibliográficos
Autores principales: Galloway, Susan, Pallebage-Gamarallage, Menuka MS, Takechi, Ryusuke, Jian, Le, Johnsen, Russell D, Dhaliwal, Satvinder S, Mamo, John CL
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359747/
https://www.ncbi.nlm.nih.gov/pubmed/18426603
http://dx.doi.org/10.1186/1476-511X-7-15