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Synergistic effects of high fat feeding and apolipoprotein E deletion on enterocytic amyloid-beta abundance
BACKGROUND: Amyloid-β (Aβ), a key protein found in amyloid plaques of subjects with Alzheimer's disease is expressed in the absorptive epithelial cells of the small intestine. Ingestion of saturated fat significantly enhances enterocytic Aβ abundance whereas fasting abolishes expression. Apolip...
Autores principales: | Galloway, Susan, Pallebage-Gamarallage, Menuka MS, Takechi, Ryusuke, Jian, Le, Johnsen, Russell D, Dhaliwal, Satvinder S, Mamo, John CL |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359747/ https://www.ncbi.nlm.nih.gov/pubmed/18426603 http://dx.doi.org/10.1186/1476-511X-7-15 |
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