The statistical analysis of a clinical trial when a protocol amendment changed the inclusion criteria

BACKGROUND: Sometimes, protocol amendments that change the inclusion and exclusion criteria are required in clinical trials. Then, the patient populations before and after the amendment may differ. METHODS: We propose to perform separate statistical tests for the different phases, i.e. for the patie...

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Detalles Bibliográficos
Autores principales: Lösch, Christian, Neuhäuser, Markus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359757/
https://www.ncbi.nlm.nih.gov/pubmed/18397525
http://dx.doi.org/10.1186/1471-2288-8-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359757/
https://www.ncbi.nlm.nih.gov/pubmed/18397525
http://dx.doi.org/10.1186/1471-2288-8-16

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