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Altered regulation of Prox1-gene-expression in liver tumors

BACKGROUND: Prospero-related homeobox 1 (Prox1) transcription factor was described as a tumor-suppressor gene in liver tumors. In contrast, Prox1 knock out in murine embryos drastically reduces proliferation of hepatoblasts. METHODS: We have studied the expression of Prox1 in normal liver, liver cir...

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Detalles Bibliográficos
Autores principales: Dudas, Jozsef, Mansuroglu, Tümen, Moriconi, Federico, Haller, Florian, Wilting, Joerg, Lorf, Thomas, Füzesi, Laszlo, Ramadori, Giuliano
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359759/
https://www.ncbi.nlm.nih.gov/pubmed/18400094
http://dx.doi.org/10.1186/1471-2407-8-92