The Metalloprotease Meprinβ Processes E-Cadherin and Weakens Intercellular Adhesion

BACKGROUND: Meprin (EC 3.4.24.18), an astacin-like metalloprotease, is expressed in the epithelium of the intestine and kidney tubules and has been related to cancer, but the mechanistic links are unknown. METHODOLOGY/PRINCIPAL FINDINGS: We used MDCK and Caco-2 cells stably transfected with meprinα...

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Detalles Bibliográficos
Autores principales: Huguenin, Maya, Müller, Eliane J., Trachsel-Rösmann, Sandra, Oneda, Beatrice, Ambort, Daniel, Sterchi, Erwin E., Lottaz, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359857/
https://www.ncbi.nlm.nih.gov/pubmed/18478055
http://dx.doi.org/10.1371/journal.pone.0002153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359857/
https://www.ncbi.nlm.nih.gov/pubmed/18478055
http://dx.doi.org/10.1371/journal.pone.0002153

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