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Genetic association studies for gene expressions: permutation-based mutual information in a comparison with standard ANOVA and as a novel approach for feature selection

Mutual information (MI) is a robust nonparametric statistical approach for identifying associations between genotypes and gene expression levels. Using the data of Problem 1 provided for the Genetic Analysis Workshop 15, we first compared a quantitative MI (Tsalenko et al. 2006 J Bioinform Comput Bi...

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Detalles Bibliográficos
Autores principales: Szymczak, Silke, Nuzzo, Angelo, Fuchsberger, Christian, Schwarz, Daniel F, Ziegler, Andreas, Bellazzi, Riccardo, Igl, Bernd-Wolfgang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359872/
https://www.ncbi.nlm.nih.gov/pubmed/18466593