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The novel microtubule-interfering agent TZT-1027 enhances the anticancer effect of radiation in vitro and in vivo
TZT-1027 is a novel anticancer agent that inhibits microtubule polymerisation and manifests potent antitumour activity in preclinical models. We have examined the effect of TZT-1027 on cell cycle progression as well as the anticancer activity of this drug both in vitro and in vivo. With the use of t...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359952/ https://www.ncbi.nlm.nih.gov/pubmed/17473826 http://dx.doi.org/10.1038/sj.bjc.6603769 |