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Mechanisms of local immunosuppression in cutaneous melanoma

Cutaneous melanoma is highly immunogenic, yet primary melanomas and metastases develop successfully in otherwise immunocompetent patients. To investigate the local immunosuppressive microenvironment, we examined the presence of suppressor T lymphocytes and tolerising dendritic cells (DCs), the expre...

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Detalles Bibliográficos
Autores principales: Polak, M E, Borthwick, N J, Gabriel, F G, Johnson, P, Higgins, B, Hurren, J, McCormick, D, Jager, M J, Cree, I A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359967/
https://www.ncbi.nlm.nih.gov/pubmed/17565341
http://dx.doi.org/10.1038/sj.bjc.6603763