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Increased chromosomal stability in cultures of ovarian tumours of low malignant potential compared to cystadenomas
Cell cultures of ovarian cystadenomas transfected with SV40 large T antigen are not immortal because they invariably reach a phenomenon called crisis, which is triggered in part by telomere attrition. Recovery from crisis may be an integral component of the malignant transformation process. We repor...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359981/ https://www.ncbi.nlm.nih.gov/pubmed/17519898 http://dx.doi.org/10.1038/sj.bjc.6603817 |