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Increased chromosomal stability in cultures of ovarian tumours of low malignant potential compared to cystadenomas

Cell cultures of ovarian cystadenomas transfected with SV40 large T antigen are not immortal because they invariably reach a phenomenon called crisis, which is triggered in part by telomere attrition. Recovery from crisis may be an integral component of the malignant transformation process. We repor...

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Detalles Bibliográficos
Autores principales: Yu, J, Roy, D, Brockmeyer, A D, Dubeau, L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359981/
https://www.ncbi.nlm.nih.gov/pubmed/17519898
http://dx.doi.org/10.1038/sj.bjc.6603817