Proteomic identification of secreted proteins as surrogate markers for signal transduction inhibitor activity

Epidermal growth factor receptor is a potential target for cancer treatment and new small-molecule tyrosine kinase inhibitor drugs have been designed to inhibit its activity. In this work we identify potential surrogate markers of drug activity using a proteomic analysis. Two-dimensional electrophor...

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Detalles Bibliográficos
Autores principales: McClelland, C M, Gullick, W J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360009/
https://www.ncbi.nlm.nih.gov/pubmed/17211472
http://dx.doi.org/10.1038/sj.bjc.6603544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360009/
https://www.ncbi.nlm.nih.gov/pubmed/17211472
http://dx.doi.org/10.1038/sj.bjc.6603544

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