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Proteomic identification of secreted proteins as surrogate markers for signal transduction inhibitor activity
Epidermal growth factor receptor is a potential target for cancer treatment and new small-molecule tyrosine kinase inhibitor drugs have been designed to inhibit its activity. In this work we identify potential surrogate markers of drug activity using a proteomic analysis. Two-dimensional electrophor...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360009/ https://www.ncbi.nlm.nih.gov/pubmed/17211472 http://dx.doi.org/10.1038/sj.bjc.6603544 |