Cargando…

In ovarian cancer the prognostic influence of HER2/neu is not dependent on the CXCR4/SDF-1 signalling pathway

HER2/neu overexpression is a driving force in the carcinogenesis of several human cancers. In breast cancer the prognostic influence of HER2/neu was shown to be at least partly based on increased metastatic potential mediated by the chemokine–chemokine receptor pair SDF-1(CXCL12)/CXCR4. We wanted to...

Descripción completa

Detalles Bibliográficos
Autores principales: Pils, D, Pinter, A, Reibenwein, J, Alfanz, A, Horak, P, Schmid, B C, Hefler, L, Horvat, R, Reinthaller, A, Zeillinger, R, Krainer, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360022/
https://www.ncbi.nlm.nih.gov/pubmed/17245339
http://dx.doi.org/10.1038/sj.bjc.6603581