Use of interfering RNA to investigate the role of endogenous gastrin in the survival of gastrointestinal cancer cells

Gastrin isoforms, acting through a variety of receptors, have proliferative and anti-apoptotic effects on gastrointestinal (GI) cancers. A small interfering RNA (siRNA) targeting the gastrin gene was used to investigate the role of endogenous gastrin in GI cancer cell survival. Downregulation of the...

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Detalles Bibliográficos
Autores principales: Grabowska, A M, Hughes, J, Watson, S A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360027/
https://www.ncbi.nlm.nih.gov/pubmed/17262081
http://dx.doi.org/10.1038/sj.bjc.6603588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360027/
https://www.ncbi.nlm.nih.gov/pubmed/17262081
http://dx.doi.org/10.1038/sj.bjc.6603588

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