Cargando…

A phase I and pharmacokinetic study of indisulam in combination with carboplatin

Indisulam (E7070) is an anticancer agent that is currently being evaluated in phase II clinical studies. A significant reduction in glutathione synthetase and glutathione reductase transcripts by indisulam provided a molecular basis for its combination with platinum agents. Indisulam demonstrated hi...

Descripción completa

Detalles Bibliográficos
Autores principales: Dittrich, C, Zandvliet, A S, Gneist, M, Huitema, A D R, King, A A J, Wanders, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360043/
https://www.ncbi.nlm.nih.gov/pubmed/17285128
http://dx.doi.org/10.1038/sj.bjc.6603606