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A phase I and pharmacokinetic study of indisulam in combination with carboplatin
Indisulam (E7070) is an anticancer agent that is currently being evaluated in phase II clinical studies. A significant reduction in glutathione synthetase and glutathione reductase transcripts by indisulam provided a molecular basis for its combination with platinum agents. Indisulam demonstrated hi...
Autores principales: | Dittrich, C, Zandvliet, A S, Gneist, M, Huitema, A D R, King, A A J, Wanders, J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360043/ https://www.ncbi.nlm.nih.gov/pubmed/17285128 http://dx.doi.org/10.1038/sj.bjc.6603606 |
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