hEGR1 is induced by EGF, inhibited by gefitinib in bladder cell lines and related to EGF receptor levels in bladder tumours

The effect of EGF and gefitinib on two EGFR-positive human bladder cancer cell lines has been investigated using array-based gene expression profiling. The most prominent transcript, increased up to 6.7-fold by EGF compared with controls in RT112 cells, was human early growth response protein 1 (hEG...

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Detalles Bibliográficos
Autores principales: Nutt, J E, Foster, P A, Mellon, J K, Lunec, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360087/
https://www.ncbi.nlm.nih.gov/pubmed/17311025
http://dx.doi.org/10.1038/sj.bjc.6603620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360087/
https://www.ncbi.nlm.nih.gov/pubmed/17311025
http://dx.doi.org/10.1038/sj.bjc.6603620

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