Overexpression of HMGA1 promotes anoikis resistance and constitutive Akt activation in pancreatic adenocarcinoma cells

HMGA1 proteins are architectural transcription factors that are overexpressed by pancreatic adenocarcinomas. Roles of HMGA1 in mediating the malignant phenotype of this cancer are poorly understood. We tested the hypothesis that overexpression of HMGA1 promotes resistance to anoikis (apoptosis induc...

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Detalles Bibliográficos
Autores principales: Liau, S-S, Jazag, A, Ito, K, Whang, E E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360112/
https://www.ncbi.nlm.nih.gov/pubmed/17342093
http://dx.doi.org/10.1038/sj.bjc.6603654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360112/
https://www.ncbi.nlm.nih.gov/pubmed/17342093
http://dx.doi.org/10.1038/sj.bjc.6603654

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