Attenuation of muscle atrophy in a murine model of cachexia by inhibition of the dsRNA-dependent protein kinase

Atrophy of skeletal muscle is due to a depression in protein synthesis and an increase in degradation. Studies in vitro have suggested that activation of the dsRNA-dependent protein kinase (PKR) may be responsible for these changes in protein synthesis and degradation. In order to evaluate whether t...

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Detalles Bibliográficos
Autores principales: Eley, H L, Russell, S T, Tisdale, M J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360141/
https://www.ncbi.nlm.nih.gov/pubmed/17387345
http://dx.doi.org/10.1038/sj.bjc.6603704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360141/
https://www.ncbi.nlm.nih.gov/pubmed/17387345
http://dx.doi.org/10.1038/sj.bjc.6603704

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