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Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy

Prognosis for patients suffering from malignant glioma has not substantially improved. Specific immunotherapy as a novel treatment concept critically depends on target antigens, which are highly overexpressed in the majority of gliomas, but the number of such antigens is still very limited. SOX2 was...

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Detalles Bibliográficos
Autores principales: Schmitz, M, Temme, A, Senner, V, Ebner, R, Schwind, S, Stevanovic, S, Wehner, R, Schackert, G, Schackert, H K, Fussel, M, Bachmann, M, Rieber, E P, Weigle, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360145/
https://www.ncbi.nlm.nih.gov/pubmed/17375044
http://dx.doi.org/10.1038/sj.bjc.6603696