Studies on p53, BAX and Bcl-2 protein expression and microsatellite instability in stage III (UICC) colon cancer treated by adjuvant chemotherapy: major prognostic impact of proapoptotic BAX

We evaluated the expression patterns of proapoptotic BAX, antiapoptotic Bcl-2 and p53, the proposed upstream effector of these molecules, as potential prognostic markers in UICC stage III colon cancer by immunohistochemical staining. To identify high-frequency microsatellite instability (MSI+) indiv...

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Detalles Bibliográficos
Autores principales: Nehls, O, Okech, T, Hsieh, C-J, Enzinger, T, Sarbia, M, Borchard, F, Gruenagel, H-H, Gaco, V, Hass, H G, Arkenau, H T, Hartmann, J T, Porschen, R, Gregor, M, Klump, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360187/
https://www.ncbi.nlm.nih.gov/pubmed/17426704
http://dx.doi.org/10.1038/sj.bjc.6603728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360187/
https://www.ncbi.nlm.nih.gov/pubmed/17426704
http://dx.doi.org/10.1038/sj.bjc.6603728

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