The hollow fibre assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells

The Hollow Fibre Assay (HFA) is usually applied as an early in vivo model for anti-cancer drug screening, but is potentially an excellent model for short-term in vivo pharmacodynamic studies. We used the model to study the in vivo role of thymidine phosphorylase/platelet-derived endothelial cell gro...

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Detalles Bibliográficos
Autores principales: Temmink, O H, Prins, H-J, van Gelderop, E, Peters, G J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360204/
https://www.ncbi.nlm.nih.gov/pubmed/17179993
http://dx.doi.org/10.1038/sj.bjc.6603507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360204/
https://www.ncbi.nlm.nih.gov/pubmed/17179993
http://dx.doi.org/10.1038/sj.bjc.6603507

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