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The hollow fibre assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells

The Hollow Fibre Assay (HFA) is usually applied as an early in vivo model for anti-cancer drug screening, but is potentially an excellent model for short-term in vivo pharmacodynamic studies. We used the model to study the in vivo role of thymidine phosphorylase/platelet-derived endothelial cell gro...

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Detalles Bibliográficos
Autores principales:	Temmink, O H, Prins, H-J, van Gelderop, E, Peters, G J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360204/ https://www.ncbi.nlm.nih.gov/pubmed/17179993 http://dx.doi.org/10.1038/sj.bjc.6603507

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