Targeting BRAF in thyroid cancer

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Activating mutations in the gene encoding BRAF are the most commonly identified oncogenic abnormalities in papillary thyroid cancer. In vitro and in vivo models have demonstrated that overexpression of activated BRAF induces malignant transformation and aggressive tumour behaviour. BRAF and other RA...

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Detalles Bibliográficos
Autores principales: Espinosa, A V, Porchia, L, Ringel, M D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360215/
https://www.ncbi.nlm.nih.gov/pubmed/17179987
http://dx.doi.org/10.1038/sj.bjc.6603520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360215/
https://www.ncbi.nlm.nih.gov/pubmed/17179987
http://dx.doi.org/10.1038/sj.bjc.6603520

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