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Cancer risks among BRCA1 and BRCA2 mutation carriers
BRCA1 and BRCA2 mutations increase breast and ovarian cancer risks substantially enough to warrant risk reduction surgery, despite variable risk estimates. Underlying this variability are methodological issues, and also complex genetic and nongenetic effects. Although many modifying factors are unid...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360226/ https://www.ncbi.nlm.nih.gov/pubmed/17213823 http://dx.doi.org/10.1038/sj.bjc.6603535 |