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Cancer risks among BRCA1 and BRCA2 mutation carriers

BRCA1 and BRCA2 mutations increase breast and ovarian cancer risks substantially enough to warrant risk reduction surgery, despite variable risk estimates. Underlying this variability are methodological issues, and also complex genetic and nongenetic effects. Although many modifying factors are unid...

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Detalles Bibliográficos
Autores principales: Levy-Lahad, E, Friedman, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360226/
https://www.ncbi.nlm.nih.gov/pubmed/17213823
http://dx.doi.org/10.1038/sj.bjc.6603535