Identification of aberrant forms of alkaline sphingomyelinase (NPP7) associated with human liver tumorigenesis

Alkaline sphingomyelinase (alk-SMase) is expressed in the intestine and human liver. It may inhibit colonic tumorigenesis, and loss of function mutations have been identified in human colon cancer. The present study investigates its expression in human liver cancer. In HepG2 liver cancer cells, RT–P...

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Detalles Bibliográficos
Autores principales: Cheng, Y, Wu, J, Hertervig, E, Lindgren, S, Duan, D, Nilsson, Å, Duan, R-D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360232/
https://www.ncbi.nlm.nih.gov/pubmed/17923876
http://dx.doi.org/10.1038/sj.bjc.6604013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360232/
https://www.ncbi.nlm.nih.gov/pubmed/17923876
http://dx.doi.org/10.1038/sj.bjc.6604013

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