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Sequential gene promoter methylation during HPV-induced cervical carcinogenesis

We aimed to link DNA methylation events occurring in cervical carcinomas to distinct stages of HPV-induced transformation. Methylation specific-multiplex ligation-dependent probe amplification (MS-MLPA) analysis of cervical carcinomas revealed promoter methylation of 12 out of 29 tumour suppressor g...

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Detalles Bibliográficos
Autores principales: Henken, F E, Wilting, S M, Overmeer, R M, van Rietschoten, J G I, Nygren, A O H, Errami, A, Schouten, J P, Meijer, C J L M, Snijders, P J F, Steenbergen, R D M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360246/
https://www.ncbi.nlm.nih.gov/pubmed/17971771
http://dx.doi.org/10.1038/sj.bjc.6604055