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Cyclooxygenase-2 overexpression abrogates the antiproliferative effects of TGF-β
The influence of cyclooxygenase-2 (COX-2) overexpression on the development of tumours has been well documented. The underlying mechanism however has still not been completely elucidated. An escape of proliferating cells from the regulatory influence of TGF-β for example in the intestine has been di...
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360247/ https://www.ncbi.nlm.nih.gov/pubmed/17955050 http://dx.doi.org/10.1038/sj.bjc.6604048 |