The therapeutic potential of a series of orally bioavailable anti-angiogenic microtubule disruptors as therapy for hormone-independent prostate and breast cancers

Therapies for hormone-independent prostate and breast cancer are limited, with the effectiveness of the taxanes compromised by toxicity, lack of oral bioavailability and drug resistance. This study aims to identify and characterise new microtubule disruptors, which may have improved efficacy relativ...

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Detalles Bibliográficos
Autores principales: Newman, S P, Foster, P A, Ho, Y T, Day, J M, Raobaikady, B, Kasprzyk, P G, Leese, M P, Potter, B V L, Reed, M J, Purohit, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360283/
https://www.ncbi.nlm.nih.gov/pubmed/18026194
http://dx.doi.org/10.1038/sj.bjc.6604100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360283/
https://www.ncbi.nlm.nih.gov/pubmed/18026194
http://dx.doi.org/10.1038/sj.bjc.6604100

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