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The therapeutic potential of a series of orally bioavailable anti-angiogenic microtubule disruptors as therapy for hormone-independent prostate and breast cancers
Therapies for hormone-independent prostate and breast cancer are limited, with the effectiveness of the taxanes compromised by toxicity, lack of oral bioavailability and drug resistance. This study aims to identify and characterise new microtubule disruptors, which may have improved efficacy relativ...
Autores principales: | Newman, S P, Foster, P A, Ho, Y T, Day, J M, Raobaikady, B, Kasprzyk, P G, Leese, M P, Potter, B V L, Reed, M J, Purohit, A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360283/ https://www.ncbi.nlm.nih.gov/pubmed/18026194 http://dx.doi.org/10.1038/sj.bjc.6604100 |
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