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Transport kinetics of four- and six-coordinate platinum compounds in the multicell layer tumour model

Four-coordinate (Pt(II)) platinum-based anticancer drugs are widely used in primary or palliative chemotherapy and produce considerable efficacy in certain clinical applications, for example testicular cancer. However, in many cancers the Pt(II) drugs are beset by poor efficacy mainly due to subopti...

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Detalles Bibliográficos
Autores principales: Modok, S, Scott, R, Alderden, R A, Hall, M D, Mellor, H R, Bohic, S, Roose, T, Hambley, T W, Callaghan, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360296/
https://www.ncbi.nlm.nih.gov/pubmed/17579620
http://dx.doi.org/10.1038/sj.bjc.6603854