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Prognostic significance of folate metabolism polymorphisms for lung cancer

Functional nonsynonymous single-nucleotide polymorphisms (nsSNPs) of folate metabolism genes can influence the methylation of tumour suppressor genes, thereby potentially impacting on tumour behaviour. To investigate whether such polymorphisms influence lung cancer survival, we genotyped 14 nsSNPs m...

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Detalles Bibliográficos
Autores principales: Matakidou, A, el Galta, R, Rudd, M F, Webb, E L, Bridle, H, Eisen, T, Houlston, R S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360297/
https://www.ncbi.nlm.nih.gov/pubmed/17533396
http://dx.doi.org/10.1038/sj.bjc.6603830