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Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy?
Gemcitabine is a deoxycytidine analogue that has a broad spectrum of antitumour activity in many solid tumours including pancreatic cancer. We have recently carried out a pharmacogenomic study in cancer patients treated with gemcitabine, and found that one genetic polymorphism of an enzyme involved...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360307/ https://www.ncbi.nlm.nih.gov/pubmed/17595663 http://dx.doi.org/10.1038/sj.bjc.6603860 |