Human MUC4 mucin induces ultra-structural changes and tumorigenicity in pancreatic cancer cells

MUC4 is a type-1 transmembrane glycoprotein and is overexpressed in many carcinomas. It is a heterodimeric protein of 930 kDa, composed of a mucin-type subunit, MUC4α, and a membrane-bound growth factor-like subunit, MUC4β. MUC4 mRNA contains unique 5′ and 3′ coding sequences along with a large vari...

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Detalles Bibliográficos
Autores principales: Moniaux, N, Chaturvedi, P, Varshney, G C, Meza, J L, Rodriguez-Sierra, J F, Aubert, J-P, Batra, S K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360313/
https://www.ncbi.nlm.nih.gov/pubmed/17595659
http://dx.doi.org/10.1038/sj.bjc.6603868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360313/
https://www.ncbi.nlm.nih.gov/pubmed/17595659
http://dx.doi.org/10.1038/sj.bjc.6603868

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