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Tissue level, activation and cellular localisation of TGF-β1 and association with survival in gastric cancer patients

Transforming growth factor-β1 (TGF-β1), a tumour suppressing as well as tumour-promoting cytokine, is stored as an extracellular matrix-bound latent complex. We examined TGF-β1 activation and localisation of TGF-β1 activity in gastric cancer. Gastric tumours showed increased stromal and epithelial t...

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Detalles Bibliográficos
Autores principales: Hawinkels, L J A C, Verspaget, H W, van Duijn, W, van der Zon, J M, Zuidwijk, K, Kubben, F J G M, Verheijen, J H, Hommes, D W, Lamers, C B H W, Sier, C F M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360315/
https://www.ncbi.nlm.nih.gov/pubmed/17637685
http://dx.doi.org/10.1038/sj.bjc.6603877