Cargando…
Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion
The c-MET receptor can be overexpressed, amplified, or mutated in solid tumours including small cell lung cancer (SCLC). In c-MET-overexpressing SCLC cell line NCI-H69, hepatocyte growth factor (HGF) dramatically induced c-MET phosphorylation at phosphoepitopes pY1230/1234/1235 (catalytic tyrosine k...
Autores principales: | Ma, P C, Tretiakova, M S, Nallasura, V, Jagadeeswaran, R, Husain, A N, Salgia, R |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360323/ https://www.ncbi.nlm.nih.gov/pubmed/17667909 http://dx.doi.org/10.1038/sj.bjc.6603884 |
Ejemplares similares
-
Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs
por: Ridolfi, E, et al.
Publicado: (2008) -
H1/pHGFK1 nanoparticles exert anti-tumoural and radiosensitising effects by inhibition of MET in glioblastoma
por: Zhang, Wenyan, et al.
Publicado: (2018) -
Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer
por: Oddo, Daniele, et al.
Publicado: (2017) -
Oxidative stress specifically downregulates survivin to promote breast tumour formation
por: Pervin, S, et al.
Publicado: (2013) -
Acute changes in liver tumour perfusion measured non-invasively with arterial spin labelling
por: Johnson, S Peter, et al.
Publicado: (2016)