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Clinical pharmacodynamic factors in docetaxel toxicity

Neutropenia is the main dose-limiting toxicity occurring in docetaxel treatment. The objective of this study was to identify pharmacodynamic (PD) factors responsible for the neutropaenia caused by docetaxel. Data were obtained from 92 patients treated with docetaxel as a monochemotherapy in two diff...

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Detalles Bibliográficos
Autores principales: Puisset, F, Alexandre, J, Treluyer, J-M, Raoul, V, Roché, H, Goldwasser, F, Chatelut, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360335/
https://www.ncbi.nlm.nih.gov/pubmed/17595656
http://dx.doi.org/10.1038/sj.bjc.6603872