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Inhibitory KIR–HLA receptor–ligand mismatch in autologous haematopoietic stem cell transplantation for solid tumour and lymphoma

Genes that encode killer Ig-like receptors (KIRs) and their HLA class I ligands segregate independently; thus, some individuals may express an inhibitory KIR gene but not its cognate ligand. We hypothesised that these patients with KIR–HLA receptor–ligand mismatch have a low risk of relapse after an...

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Detalles Bibliográficos
Autores principales: Leung, W, Handgretinger, R, Iyengar, R, Turner, V, Holladay, M S, Hale, G A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360345/
https://www.ncbi.nlm.nih.gov/pubmed/17667923
http://dx.doi.org/10.1038/sj.bjc.6603913