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Targeting HER proteins in cancer therapy and the role of the non-target HER3

Members of the human epidermal growth factor receptor (HER) family have been of considerable interest in the cancer arena due to their potential to induce tumorigenesis when their signalling functions are deregulated. The constitutive activation of these proteins is seen in a number of different com...

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Detalles Bibliográficos
Autores principales: Hsieh, A C, Moasser, M M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360352/
https://www.ncbi.nlm.nih.gov/pubmed/17667926
http://dx.doi.org/10.1038/sj.bjc.6603910