Cargando…

PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound

Rhabdomyosarcoma (RMS) is the most common paediatric soft-tissue sarcoma including two major subtypes, alveolar rhabdomyosarcoma (ARMS) and embryonal rhabdomyosarcoma (ERMS). Increasing evidence suggests that oncogenesis of RMS involves multistages of signalling protein dysregulation which may inclu...

Descripción completa

Detalles Bibliográficos
Autores principales: Cen, L, Hsieh, F-C, Lin, H-J, Chen, C-S, Qualman, S J, Lin, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360380/
https://www.ncbi.nlm.nih.gov/pubmed/17848913
http://dx.doi.org/10.1038/sj.bjc.6603952