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PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound

Rhabdomyosarcoma (RMS) is the most common paediatric soft-tissue sarcoma including two major subtypes, alveolar rhabdomyosarcoma (ARMS) and embryonal rhabdomyosarcoma (ERMS). Increasing evidence suggests that oncogenesis of RMS involves multistages of signalling protein dysregulation which may inclu...

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Detalles Bibliográficos
Autores principales:	Cen, L, Hsieh, F-C, Lin, H-J, Chen, C-S, Qualman, S J, Lin, J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360380/ https://www.ncbi.nlm.nih.gov/pubmed/17848913 http://dx.doi.org/10.1038/sj.bjc.6603952

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