In vitro evaluation of cancer-specific NF-κB-CEA enhancer–promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines

Nuclear factor-kappa B (NF-κB) is a transcription factor with high transcriptional activity in cancer cells. In this study, we developed a novel enhancer–promoter system, κB4-CEA205, in which the basal carcinoembryonic antigen (CEA) promoter sequence (CEA205) was placed downstream of the four tandem...

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Detalles Bibliográficos
Autores principales: Guo, X, Evans, T R J, Somanath, S, Armesilla, A L, Darling, J L, Schatzlein, A, Cassidy, J, Wang, W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360387/
https://www.ncbi.nlm.nih.gov/pubmed/17687334
http://dx.doi.org/10.1038/sj.bjc.6603930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360387/
https://www.ncbi.nlm.nih.gov/pubmed/17687334
http://dx.doi.org/10.1038/sj.bjc.6603930

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