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In vitro evaluation of cancer-specific NF-κB-CEA enhancer–promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines

Nuclear factor-kappa B (NF-κB) is a transcription factor with high transcriptional activity in cancer cells. In this study, we developed a novel enhancer–promoter system, κB4-CEA205, in which the basal carcinoembryonic antigen (CEA) promoter sequence (CEA205) was placed downstream of the four tandem...

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Detalles Bibliográficos
Autores principales:	Guo, X, Evans, T R J, Somanath, S, Armesilla, A L, Darling, J L, Schatzlein, A, Cassidy, J, Wang, W
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360387/ https://www.ncbi.nlm.nih.gov/pubmed/17687334 http://dx.doi.org/10.1038/sj.bjc.6603930

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