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Genetic variation in five genes important in telomere biology and risk for breast cancer

Telomeres, consisting of TTAGGG nucleotide repeats and a protein complex at chromosome ends, are critical for maintaining chromosomal stability. Genomic instability, following telomere crisis, may contribute to breast cancer pathogenesis. Many genes critical in telomere biology have limited nucleoti...

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Detalles Bibliográficos
Autores principales: Savage, S A, Chanock, S J, Lissowska, J, Brinton, L A, Richesson, D, Peplonska, B, Bardin-Mikolajczak, A, Zatonski, W, Szeszenia-Dąbrowska, N, Garcia-Closas, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360388/
https://www.ncbi.nlm.nih.gov/pubmed/17848914
http://dx.doi.org/10.1038/sj.bjc.6603934