Enhanced repair of DNA interstrand crosslinking in ovarian cancer cells from patients following treatment with platinum-based chemotherapy

Despite high tumour response rates to platinum-based chemotherapy in ovarian cancer survival is poor due to the emergence of drug resistance. Mechanistic studies in clinical material have been hampered by the unavailability of sensitive methods to detect the critical drug-induced effects in individu...

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Detalles Bibliográficos
Autores principales: Wynne, P, Newton, C, Ledermann, J A, Olaitan, A, Mould, T A, Hartley, J A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360410/
https://www.ncbi.nlm.nih.gov/pubmed/17848946
http://dx.doi.org/10.1038/sj.bjc.6603973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360410/
https://www.ncbi.nlm.nih.gov/pubmed/17848946
http://dx.doi.org/10.1038/sj.bjc.6603973

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