In vitro and in vivo reversal of resistance to 5-fluorouracil in colorectal cancer cells with a novel stealth double-liposomal formulation

Drug resistance is a major cause of treatment failure in cancer chemotherapy, including that with the extensively prescribed antimetabolite, 5-fluorouracil (5-FU). In this study, we tried to reverse 5-FU resistance by using a double-punch strategy: combining 5-FU with a biochemical modulator to impr...

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Detalles Bibliográficos
Autores principales: Fanciullino, R, Giacometti, S, Mercier, C, Aubert, C, Blanquicett, C, Piccerelle, P, Ciccolini, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360412/
https://www.ncbi.nlm.nih.gov/pubmed/17848948
http://dx.doi.org/10.1038/sj.bjc.6603970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360412/
https://www.ncbi.nlm.nih.gov/pubmed/17848948
http://dx.doi.org/10.1038/sj.bjc.6603970

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