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Molecular consequences of SOD2 expression in epigenetically silenced pancreatic carcinoma cell lines
Manganese superoxide dismutase (SOD2) is an enzyme that catalyses the dismutation of superoxide in the mitochondria, leading to reduced levels of reactive oxygen species. Reduced expression levels of SOD2 have been shown to result in increased DNA damage and sod2 heterozygous mice have increased inc...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360443/ https://www.ncbi.nlm.nih.gov/pubmed/17895890 http://dx.doi.org/10.1038/sj.bjc.6604000 |